AM-2201 crystal AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor. AM-2201 crystal is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern University.
AM-2201 is a full agonist for cannabinoid receptors. Affinities are: with a Ki of 1.0 nM at CB1 and 2.6 nM at CB2. The 4-methyl functional analog MAM-2201 probably has similar affinities. AM-2201 has an EC50 of 38 nM for human CB1 receptors, and 58 nM for human CB2 receptors. AM-2201 produces bradycardia and hypothermia in rats at doses of 0.33 mg/kg, comparable to the potency of JWH-018 in rats, suggesting potent cannabinoid-like activity.
AM-2201 crystal
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AM-2201 crystal AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor. AM-2201 crystal is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern University.
AM-2201 is a full agonist for cannabinoid receptors. Affinities are: with a Ki of 1.0 nM at CB1 and 2.6 nM at CB2. The 4-methyl functional analog MAM-2201 probably has similar affinities. AM-2201 has an EC50 of 38 nM for human CB1 receptors, and 58 nM for human CB2 receptors. AM-2201 produces bradycardia and hypothermia in rats at doses of 0.33 mg/kg, comparable to the potency of JWH-018 in rats, suggesting potent cannabinoid-like activity.
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100grams, 250grams, 500grams, 1 kilogram |
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Product details
Common Name DL-Tartaric acid
CAS Number 133-37-9
Density 1.9Ā±0.1 g/cm3
Boiling Point 399.3Ā±42.0 Ā°C at 760 mmHg
Melting Point 200-206ĀŗC
Molecular Formula C4H6O6
Molecular Weight 150.087
Flash Point 209.4Ā±24.4 Ā°C
Exact Mass 150.016434
LogP -1.43
PSA 115.06000
Vapour Pressure 0.0Ā±2.1 mmHg at 25Ā°C
Index of Refraction 1.586
Stability Stable. Incompatible with bases, oxidizing agents, reducing agents, silver.
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Ketamine Hcl Crystal
Ketamine Hcl Crystal
- Ketamine is a medication mainly used forĀ starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain, sedation in intensive care, and depression.
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- Ketamine is a medication mainly used forĀ starting and maintaining anesthesia. It induces a trance-like state while providing pain relief, sedation, and memory loss. Other uses include for chronic pain, sedation in intensive care, and depression.
- KetamineĀ is frequently used in severely injured people and appears to be safe.
- A clinical practice guideline supports the use of ketamine as a dissociative sedative in emergency medicine.
- It is the drug of choice for people in traumatic shockĀ who are at risk of hypotension.
- Low blood pressure is harmful toĀ people with severe head injury and ketamine is least likely to cause low blood pressure, often even able to prevent it.
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Synonyms
AM2201 indazole analog
5-fluoropentyl JWH 018 indazole analog
5-fluoro THJ 018
Technical Information
Formal Name
[1-(5-fluoropentyl)-1H-indazol-3-yl]-1-naphthalenyl-methanone
CAS Number
1801552-01-1
Molecular Formula
C23H21FN2O
Formula Weight
360.4
Purity
ā„98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/ml
DMSO: 5 mg/ml
Ī»max
219, 320 nm
SMILES
O=C(C1=CC=CC2=C1C=CC=C2)C3=NN(CCCCCF)C4=C3C=CC=C4
InChi Code
InChI=1S/C23H21FN2O/c24-15-6-1-7-16-26-21-14-5-4-12-20(21)22(25-26)23(27)19-13-8-10-17-9-2-3-11-18(17)19/h2-5,8-14H,1,6-7,15-16H2
InChi Key
DULWRYKFTVFPTL-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20Ā°C
Shipping
Room TemperatureĀ in continental US; may vary elsewhere
Stability
ā„Ā 5 years
Ketamine Powder
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Ketamine sold under the brand name Ketalar among others is a medicine mainly used for starting and maintaining anesthesia. K is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, produced minor hallucinogenic effects and shorter psychotomimetic effects. This product was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.Uses
It is used before surgery or a medical or dental procedure to produce a loss of consciousness. This medicine is a type of anesthetic. When used recreationally, it can be ingested by mouth in pill or capsule form. In liquid form, it can be injected into a vein, consumed in beverages, or added to smokable materials. Some people also inject the drug intramuscularly.WHAT DO I NEED TO KNOW BEFORE TAKING IT?
Some medical conditions may interact withĀ Ketamine Powder. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: WHAT IS KETAMINE? Ketamine is a dissociative anesthetic that has some hallucinogenic effects. It distorts perceptions of sight and sound and makes the user feel disconnected and not in control. It is an injectable, short-acting anesthetic for use in humans and animals. It is referred to as a ādissociative anestheticā because it makes patients feel detached from their pain and environment. Ketamine can induce a state of sedation (feeling calm and relaxed), immobility, relief from pain, and amnesia (no memory of events while under the influence of the drug). It is abused for its ability to produce dissociative sensations and hallucinations. Ketamine has also been used to facilitate sexual assault. WHAT IS ITS ORIGIN? Ketamine is produced commercially in a number of countries, including the United States. Most of the ketamine illegally distributed in the United States is diverted or stolen from legitimate sources, particularly veterinary clinics, or smuggled into the United States from Mexico. Distribution of ketamine typically occurs among friends and acquaintances, most often at raves, nightclubs, and at private parties; street sales of ketamine are rare. How is it abused? Ketamine, along with the other āclub drugs,ā has become popular among teens and young adults at dance clubs and āraves.ā Ketamine is manufactured commercially as a powder or liquid. Powdered ketamine is also formed from pharmaceutical ketamine by evaporating the liquid using hot plates, warming trays, or microwave ovens. What are common street names? Common street names include: ā¢ Cat Tranquilizer, Cat Valium, Jet K, Kit Kat, Purple, Special K, Special La Coke, Super Acid, Super K, and Vitamin K What does it look like? Ketamine comes in a clear liquid and a white or off-white powder. Powdered ketamine (100 milligrams to 200 milligrams) typically is packaged in small glass vials, small plastic bags, and capsules as well as paper, glassine, or aluminum foil folds. Powdered ketamine is cut into lines known as bumps and snorted, or it is smoked, typically in marijuana or tobacco cigarettes. Liquid ketamine is injected or mixed into drinks. Ketamine is found by itself or often in combination with MDMA, amphetamine, methamphetamine, or cocaine.
N-Ethylhexedrone Crystal,NEH (HEXEN)
Abstract and figures
N-ethylhexedrone (HEX-EN) is a synthetic cathinone, a hexedrone derivative, which is structurally close to other popular cathinones such as pentedrone and Ī±-pyrrolidinohexiophenone (Ī±-PHP). This substance appeared in Europe in October 2015, and it was detected in biological material for the first time at the Institute of Forensic Research in Krakow at the beginning of 2017. The article presents three cases in which the presence of N-ethylhexedrone in the blood of drivers was revealed. The use of liquid chromatography-mass spectrometry with different mass analyzers and in-depth analysis of mass spectra enabled the detection and identification of this compound, which was not covered by previously applied screening method. Liquid-liquid extraction was used for the isolation of N-ethylhexedrone from blood samples. The developed liquid chromatography-linear ion trap-mass spectrometry (LC-LIT-MS) method was successfully applied in the determination of N-ethylhexedrone. Blood concentrations of this compound ranged from 8 to 37 ng/ml. Despite the lack of clear symptoms in the reported driving cases, the N-ethylhexedrone effects reported on the Internet forums suggest that driving under the influence of this substance should be treated as a potential threat to traffic safety.
Introduction
n-ethylhexedrone (2-(ethylamino)-1-phenylhex-
an-1-one; Ī±-ethylaminohexanophenone) is a synthetic
cathinone, a derivative of hexedrone, in which the me-
thyl group attached to the nitrogen atom is substituted
by an ethyl group (Fig. 1). Structurally it is similar
to pentedrone, and also Ī±-pyrrolidinohexiophenone
(Ī±-PHP), from which it differs by the substitution of
a pyrrolidine group with an n-ethyl group. it is most
commonly referred to as HeX-en, ethyl-Hex and
neH by users (internationally), as well as Henio and
Henryk by Polish users. n-ethylhexedrone was de-
scribed for the first time in 1964 together with other
derivatives of aminoketone in a patent by Boehringer
ingelheim (Patent: GB1069797, 1964). This sub-
stance appeared in europe in october 2015 and was
frequently detected in the following year (eMcdda).
its presence in Poland was probably a response to the
amendment of the act of 29 july 2005 on counteract-
ing drug addiction (journal of Laws 2005 no. 179
item 1485, with later amendments), which entered into
force on 1 july 2015. on that date, another 114 new
psychoactive substances (nPS) were placed on sched-
ules of controlled substances, amongst them popular
cathinones ā Ī±-PVP and pentedrone, as well as hexe-
drone. nPS that are encompassed by legal control are
immediately replaced by their new, uncontrolled.
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